Background: Hypertension and Type 2 Diabetes Mellitus prevalence's are increased in Iraq. Patient compliance to treatment is a factor in the outcome of medical treatment. Objectives: Assess Resafa sector PHCs Hypertension and type 2 Diabetes Mellitus patients' compliance for treatment- drug and its factors. Methodology: cross sectional study with analytic element, was conducted by involved of hypertension and type 2 Diabetes Mellitus patients in al-Resafa sector PHCs. Three hundred patients were involved in this study by using 3 different scales Morisky compliance scale/ self report, Pill identification test, and tablet account to assess their compliance. Blood pressure and blood sugar, height and weight measured for each. Results: out of 300 patients, 148 patient with HT, 76 patient with NIDM, 76 patients have both, most of participants 103(34.3%) aged 50-59 yrs, 217(72.3%) female, 100(33.3%) primary educational level, 242(80.7%) currently married, diagnosed since 1-6 years of the study, 143(47.7%)receive good counseling, 249(83%) modified their lifestyle, Morisky scale show 113(38.43%) low compliance, while tablet accounts 221(75.17%), pills identification 264(89.79%) show good compliance, and 108(36.73%) overall compliance was medium, 66% patients had uncontrolled blood pressure, 64% uncontrolled blood sugar, 50% obese, and 26% lost weight. Conclusion: Near one third of the respondents had good overall compliance &two thirds of them had uncontrolled hypertension as well as NIDM, and half of them obese.