This paper deals with “Fatigue Analysis of Aluminum Alloy Wheel under various RPMs”. During the part of project a static and fatigue analysis of aluminum alloy wheel was carried out using FEA package. The 3-dimensional model of the wheel was designed using UG (NX). Then the 3-D model was imported into ANSYS using the IGES format. The finite element idealization of this model was then produced. The analysis was performed in a static condition. This is constrained in all degree of freedom at the PCD and hub portion. The wheel is subjected to various RPMs. We find out the total deformation, alternative stress and shear stress by using FEA software. And also we find out the life, safety factor and fatigue sensitivity of alloy wheel.