Moringa oleifera commonly known as Moringa is an exceptionally nutritious vegetable tree with a variety of potentially medicinal importance, it is even termed as Miracle tree due to the various applications it posses. This present study was designed to investigate the antimicrobial and antioxidant activity of Moringa oleifera leaf extract dissolve in different solvents (Aqueous, Hydroethanolic and Hydromethanolic) at different concentrations, and also to analyze the presence of Phytochemicals. The phytochemical screening indicates the presence of Alkaloids, Terpenoids, Cardiac glycoside, Flavanoid, Phenol, and Tannins among others. The leaf extract shows a broad spectrum of antibacterial and antifungal activity on potentially phathogenic microorganism including Escherichia coli, Staphylococcus aureus, Klebciella species and Candida albican at different concentrations of extract. Maximum zone of inhibition was found to be 13.30 mm and 9.00 mm and the minimum zone of inhibition was found to be 7.60 mm and 8.60 mm in both bacterial and fungal strains respectively. Hydroethanolic extract was found to have the maximum zone of inhibition of 13.30 mm at concentration of 1000 µg/ml in Escherichia coli and minimum zone of inhibition to be 7.6 mm in Escherichia coli at concentration of 750 µg/ml. Also the plant shows antioxidant activity with decrease in DPPH concentration due to scavenging activity of MO extract. The scavenging effect of MO extracts on DPPH was found to be 63.12% at 1000 µg/ml compare with the standard BHA 86.9%. In H2O2 the highest % inhibition of MO was found to be 74% compared with standard BHA 91% thus this shows that MO leaf extract have hydrogen scavenging activity and also reducing power capacity was observed with increase in concentration and absorbance.