Indigenous knowledge is the systematic body of knowledge acquired by the local people through the accumulation of experience informal experiments and intimate understanding of the environment. It is strongly believed that indigenous knowledge practices pave way for sustainable development. Indigenous knowledge is offering sustainable approaches to agriculture and rural development. (Chambers, 1983 and Waren, 1989). Indian tribal regions are noted for their rich indigenous wisdom. Considering the significance of indigenous knowledge system an attempt was made to identify the various indigenous agricultural practices in the tribal regions of Pachaimalai Hills in Tamil Nadu. Indigenous practices like the use of neem, neem oil etc. for the control of pest and diseases, use of ash for controlling the crop pests, use of indigenous storage structures like ‘Kudhir’ and mud pots, use of indigenously made tools to control the rats use of dried neem leaves in sorghum for controlling storage pests, were identified in the study area. Constraints like no recognition, no reward, and neglect by elite people that resist the effective utilization of indigenous practices were also observed and reported.