Palliative care is a specialized care area committed to deliver health care facilities to the patients with life-limiting illnesses (cancer, neurodegenerative disease, dementia) for prevention and relief of suffering, relieving pain and distress and to attain best possible quality of life for patient and their family. Palliative care aimed to impart holistic and client centred approach to relieve from pain and psychological, spiritual and emotional issues of patients and families. Palliative care is delivered by specially trained professionals such as Doctors, nurses, social workers, dietician, therapist and home health care groups. they incorporate together to meeting the need of clients and families for better client outcome. The utmost concern of client with terminal illness such as cancer is to sustenance quality of life and prolongation of survival. Patient with cancer encounter psychological issues mainly fear, stress, tension, physiological issues; nausea, vomiting, weakness, hair loss and social issue such as dependence role, social isolation and stigma. This article mainly reflecting the holistic need of cancer patient by introducing early palliative care approach for promoting comfort safeguarding patients.