Anthropometric analysis of palpebral and interpupillary dimension is very important to maxillofacial and plastic surgeons, anthropologist, dysmorphologists and in forensic investigations. The study was carried on the Anthropometric analysis of palpebral and interpupillary among Northern Cross River State ethnic population. A total number of five hundred subjects, two hundred and fifty (250) males and two hundred and fifty (250) females between age group 10-49years, were randomly selected from primary and secondary schools, villages and towns within the Northern Cross River extraction. Obtained data was analyzed and there were found statistically significant (p<0.05).The results showed that the HPA is significantly higher in males than in females. There was significant difference in IPD between males and females. The near interpupillary distance (NIPD) and far interpupillary distance (FIPD) values were significantly higher (P<0.05) in males than in females. There was significant (p<0.05) sexual dimorphism. The result drawn from this study could be use immense by maxillofacial and plastic surgeons, anthropologist, dysmorphologists and in forensic investigations.